Ocugen, Inc.

Pursuing Innovative Ocular Biotherapeutics

Our mission is to develop innovative therapies to address rare and underserved eye diseases

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Pursuing Innovative Ocular Biotherapeutics

Ocugen, Inc. is a clinical stage biopharmaceutical company focused on discovering, developing and commercializing a pipeline of innovative therapies that address rare and underserved eye diseases. The Company offers a robust and diversified ophthalmology portfolio that includes novel gene therapies, biologics, and small molecules and targets a broad range of high-need retinal and ocular surface diseases. Ocugen is leveraging its groundbreaking modifier gene therapy platform to address genetically diverse inherited retinal disorders, including its therapies based on the nuclear hormone receptor genes NR2E3 (OCU400) and RORA (OCU410). Ocugen is also developing novel biologic therapies for wet-AMD, DME and diabetic retinopathy (OCU200), as well as for retinitis pigmentosa (OCU100). The Company's late-stage clinical pipeline offers near-term revenue potential with two candidates currently in Phase 3 trials for patients with ocular surface diseases, including ocular graft versus host disease (oGVHD) (OCU300) and dry eye disease (OCU310). Both OCU300 and OCU310 leverage Ocugen’s patented OcuNanoE – Ocugen’s ONE Platform™ technology to enhance the efficacy of topical ophthalmic therapeutics. OCU300 is the first and only therapeutic with orphan drug designation for oGVHD, providing certain regulatory and economic benefits.

Explore our pipeline of therapies targeting underserved areas of ophthalmology:

  • OCU300
    For ocular graft versus host disease (oGVHD)
  • OCU310
    For treatment of dry eye disease (DED)
  • OCU400
    For treatment of inherited retinal disorders utilizing gene therapy
  • OCU200
    For wet age-related macular degeneration

Addressing a common complication that occurs in about 60% of patients who have undergone allogeneic hemotological stem cell transplantation, or bone marrow transplants.

Learn More About OCU300

Addressing a common yet under-diagnosed ocular disorder that affects millions of adults in the US and its prevalence increases with age.

Learn More About OCU310

Addressing a range of genetically diverse inherited degenerative retinal diseases.

Learn More About OCU400

Addressing a group of inherited diseases that cause progressive retinal degeneration, affecting approximately 100,000 people in the US and similar number in Europe.

Learn More About OCU100

Addressing the leading cause of vision loss in people over the age of 60, where abnormal blood vessels grow under the retina and leak blood and proteins.

Learn More About OCU200

Press Releases

Explore our pipeline of therapies targeting underserved areas of ophthalmology:

OCU300
For ocular graft versus host disease (oGVHD)

Addressing a common complication that occurs in 40-60% of patients who have undergone allogenic hemotological stem cell transplantation, or bone marrow transplants.

Learn More About OCU300

OCU310
For treatment of dry eye disease (DED)

Addressing a common yet under-diagnosed ocular disorder that affects millions of adults in the US and its prevalence increases with age.

Learn More About OCU310

OCU400
For treatment of inherited retinal disorders utilizing gene therapy

Addressing a range of genetically diverse inherited degenerative retinal diseases.

Learn More About OCU400
OCU200
For wet age-related macular degneration

Addressing the leading cause of vision loss in people over the age of 60, where abnormal blood vessels grow under the retina and leak blood and proteins.

Learn More About OCU200

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